Decoding the Rapid Growth of Bamboo via Single-Cell Spatiotemporal Atlas
Our recent study in PNAS leverages Stereo-seq to provide the first high-resolution characterization of intercalary me...
Read More →XinLab has steadily advanced genomics research across diverse fields—from plant genome evolution to innovations in single‐cell and spatial omics, as well as collaborative projects in marine biology, clinical disease research, and agricultural genomics. These accomplishments underscore our commitment to refining methods, enhancing data analysis, and delivering meaningful applications—all in line with our mission to contribute to the genomics field. We also share our insights on some of the most intriguing recent studies, which we categorize as "frontiers."
Nature: A Multilineage Organoid Model of the Human Stomach - Breakthrough: Human Gastroids Model Self-Organized Patterning in Stomach Development
Our recent study published in Nature introduces “Human Gastroids”—multilineage organoids that recapitulate the comple...
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Exploring Antarctic Krill Mitogenomes: Insights into Genetic Diversity and Population Dynamics
Antarctic krill (Euphausia superba), a keystone species in the Southern Ocean ecosystem, plays a pivotal role in glob...
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Tertiary Lymphoid Organ-like Structures in Carotid Artery Plaques: A Breakthrough in Understanding Plaque Instability
Tertiary lymphoid organ-like structures in human atherosclerosis contribute to plaque instability. Xin Liu, on behalf...
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Single‐Cell Multiome Reveals Root Hair‐Specific Responses to Salt Stress in Non‐Heading Chinese Cabbage
Our recent paper introduced findings on mechanisms underlying salt-tolerance in non-heading Chinese cabbage using sin...
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New RNA-seq Analysis Method - TRADE
In a recent Nature paper, a novel RNA-seq analysis method was published, which might be the future direction for RNA-...
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Sensitively detect cfRNA - RARE-seq
In a recent Nature paper, an improved sequencing method to more sensitively detect cell-free RNA was reported.
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Review Article on Spatial Omics for Plant Research
Our recent review paper comprehensively introduced spatial transcriptome technologies and their applications in plant...
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Soybean Transcriptomic Atlas
We generated Bulk, Single-Cell, and Spatial Transcriptome Data for Soybean to Unveil Mechanisms Underlying its Organ ...
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Breaking Boundaries! Mice Exhibit 'Rescue' Behavior, Redefining Animal Social Cognition
A groundbreaking study published in *Science unveils how mice exhibit complex rescue behaviors toward unconscious pee...
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New Paper Unveils Spatiotemporal Atlas of Mouse Heart Development
We’re thrilled to announce that XinLab has published a new paper in GigaScience (2025, Vol. 14) titled “Exploring the...
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Lamprey Cell Atlas Study Reveals Natterin's Role in Fat Browning
A study co-led by Xin Liu (BGI Research / XinLab), Guangyi Fan (BGI Research), Qingwei Li (Liaoning Normal University...
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Conserved Chloroplast Genomes of Heliconia Revealed
We’re excited to share that XinLab has published a new study in Frontiers in Plant Science (2025, Vol. 15) titled “Un...
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Decoding the Genomic and Cis-Regulatory Basis of Plastic C3-C4 Photosynthesis
Our recent study reveals how Eleocharis baldwinii switches between C3 and C4 photosynthesis through environmentally-t...
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Cell Article: Genomic Insights into the Population Dynamics and Adaptation of Hadal Amphipods
Our recent study in Cell, based on the genomes of over 600 deep-sea amphipods, reveals how host-symbiont interactions...
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Dynamic TE Shaping Plant Evolution and Crop Traits
We analyzed 811 plant genomes across 119 species to create an unprecedented atlas of recent transposable element acti...
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Multi-omics Landscape and Molecular Basis of Radiation Tolerance in a Tardigrade
In our latest collaborative project, we delved deep into the molecular basis of radiation tolerance in a newly identi...
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Massive Genomic Study Catalogues Marine Microbes
🌊 BGI Research Team Unveils Vast Marine Microbial Diversity and Biotechnological Potential in Nature and successfully...
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mtscATAC-seq based on DNBelab C4 published
Our recent paper in Aging Cell described our recently developed single-cell mitochondrial sequencing methods. Here we...
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Mapping Drought Tolerance in Chickpea: Insights from Whole Genome Resequencing of a MAGIC Population
In our ongoing long-term collaboration with Dr. Rajeev Varshney, our team has taken a further step forward in underst...
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Chromosome-Scale Genome of Chitala ornata Illuminates Early Teleost Evolution
Chromosome-Scale Genome of Chitala ornata Illuminates Early Teleost Evolution
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Cicer Super-Pangenome Study Offers Insights for Chickpea Improvement
Published online in Nature Genetics on May 23, 2024, a study presents genomes of eight wild chickpea relatives and a ...
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Rattan Phylogeny based on the Calamus tetradactylus Chloroplast Genome
Our recent study published in BMC Genomic Data by Zhang et al. provides the first complete chloroplast genome sequenc...
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Cellular and Molecular Insights into Fibrosis and Resolution in the Bleomycin-Induced Pulmonary Fibrosis Mouse Model
Pulmonary fibrosis is a chronic lung condition with limited treatment options and significant mortality rates. To bet...
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Genomic Features and Genetic Basis of Tooth Development in Characiformes
Fish, as the most ancient vertebrates, exhibit many unique characteristics compared to later-evolving vertebrates. Ou...
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Chromosome-Level Genome of Butterflyfish Reveals Unique Color Patterns and Morphological Features
Butterflyfishes (family Chaetodontidae) are iconic reef dwellers, renowned for their vibrant color patterns and speci...
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Chromosome-Level Antarctic Krill Genome Unlocks Insights into Adaptations and Population Dynamics
Antarctic krill (Euphausia superba), Earth’s most abundant wild animal, plays a pivotal role in the Southern Ocean ec...
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Symbiont-Screener: Efficient Separation of Host and Symbiont Sequences for Long-Read Metagenomics
The phenomenon of symbiosis is widespread in nature, with biological samples often containing data from multiple spec...
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A Comprehensive Chickpea Genetic Variation Map: Insights from 3,366 Genomes
Chickpea (Cicer arietinum), one of the world’s most important legume crops, has long been a focal point in agricultur...
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Chromosome-Level Genome Assembly of Fall Armyworm Sheds Light on Its Invasion and Pesticide Resistance
Fall armyworm (Spodoptera frugiperda) is a highly destructive pest that has rapidly spread across multiple continents...
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Microbial Diversity in Industrial Effluents: Unlocking Source Tracking Potential
Understanding the microbial diversity in industrial effluents is crucial for efficient environmental surveillance and...
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Unveiling the Genetic Diversity of Moso Bamboo: A Population Genomics Study
Bamboo has been an integral part of Chinese culture and daily life for centuries, serving not only as an essential na...
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Comparative Analysis of Clonal Evolution in Right- and Left-Sided Colon and Rectal Cancer
Tumor evolution is a dynamic and complex process, with variations in growth patterns significantly influencing diseas...
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Deciphering the Evolution of Neo-Y Chromosomes: Insights from the Spotted Knifejaw Genome
Sex chromosome evolution is one of the most fascinating processes in genomic research, with profound implications for...
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Global Lettuce Genomics: Unraveling the Domestication History and Genetic Diversity of Cultivated Lettuce
Lettuce (Lactuca sativa) is one of the most widely consumed leafy vegetables in the world, yet its genetic diversity ...
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Genomic Insights into Mangrove Rhizosphere Fungi: Understanding Microbial Adaptations in Coastal Ecosystems
Mangrove forests are among the most biologically diverse and ecologically productive ecosystems, hosting a rich array...
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SLR-superscaffolder: A Novel Scaffolding Tool for Synthetic Long Reads
Genome assembly is a fundamental component of genomics research, enabling the reconstruction of complete genetic sequ...
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Metagenomic Analysis Reveals Microbial Community Structure and Nitrogen Acquisition Strategies in the Indian Ocean
Despite being the third-largest ocean in the world, the Indian Ocean remains one of the least studied regions in term...
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Accurate Haplotype-Resolved Assembly in Human Trios Using Long Fragment Read Sequencing
Understanding how genetic variations are inherited and structured within an individual’s genome is key to advancing p...
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Chromosome-Level Genome Assembly of White-Spotted Bamboo Shark: Insights into Evolution and Immunity
Cartilaginous fish, such as sharks, represent an early branch in vertebrate evolution, offering valuable insights int...
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African Arowana Genome Provides Insights into Ancient Teleost Evolution
The evolutionary history of teleosts is deeply intertwined with continental drift, shaping their genetic diversity an...
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Deciphering the Microbial Taxonomy and Functionality of Mangrove Ecosystems
Mangrove ecosystems are unique coastal environments that support diverse microbial communities, playing a crucial rol...
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Chromosome-Level Genome Assembly of Indo-Pacific Humpback Dolphin
The Indo-Pacific humpback dolphin (Sousa chinensis) is a coastal cetacean species facing increasing threats due to ha...
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Chromosome-Level Genome Assembly and GWAS for Panax Notoginseng
Panax notoginseng (P. notoginseng), a medicinal herb with significant economic and therapeutic value, has long been s...
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Comparative Chloroplast Genomics of Mangrove Species: Phylogenetic Insights and Evolutionary Analysis
Mangrove ecosystems serve as critical environmental buffers between land and sea, hosting unique plant species that h...
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Genome Sequencing of Mekong Tiger Perch: Insights into Phylogeny and Conservation
The Mekong tiger perch (Datnioides undecimradiatus) is a vulnerable freshwater fish native to the Mekong basin in Ind...
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Lineage-Specific Evolution of Mangrove Plastid Genomes
Mangrove forests thrive in coastal tropical and subtropical regions, bridging the gap between terrestrial and marine ...
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Genomes of Early-Diverging Streptophyte Algae Shed Light on Plant Terrestrialization
The transition of plants from aquatic to terrestrial environments represents a pivotal moment in evolutionary history...
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Chromosome-Based Rubber Tree Genome Provides Insights into Evolution and Rubber Biosynthesis
The rubber tree (Hevea brasiliensis) is the primary source of natural rubber, a crucial industrial material with no s...
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Draft Genomes of Jackfruit and Breadfruit Provide Insights into Starch and Sugar Metabolism
Jackfruit (Artocarpus heterophyllus) and breadfruit (Artocarpus altilis) are two economically and nutritionally signi...
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Chromosome-Level Genome Assembly of Mangrove Fungus Penicillium variabile HXQ-H-1
Mangrove ecosystems host a diverse range of microorganisms, including fungi that play a crucial role in organic matte...
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Draft Genome Sequence of Solanum Aethiopicum: Advancing Disease Resistance and Drought Tolerance Research
The African eggplant (Solanum aethiopicum) is a vital crop cultivated across tropical Africa for its nutritional and ...
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Resequencing 545 Ginkgo Genomes: Unveiling the Evolutionary History of a Living Fossil
As one of the most ancient living plants, Ginkgo biloba has survived for over 200 million years, maintaining its resi...
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Exploring the Commensal Microbiome of the Sperm Whale
The commensal microbiota of marine mammals plays a crucial role in their health and adaptation to the oceanic environ...
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Resequencing 429 Chickpea Accessions: Insights into Genome Diversity and Domestication
Chickpea (Cicer arietinum) is a staple legume crop with immense nutritional and agricultural importance. Understandin...
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Chromosome-Level Genome Assembly of Sperm Whale: Insights into Marine Mammal Evolution
Marine mammals offer unique evolutionary models, demonstrating adaptations to aquatic environments through physiologi...
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Chromosome-Level Genome Assembly of Black Rockfish Provides Insights into the Evolution of Live Birth
The black rockfish (Sebastes schlegelii) is a teleost species that exhibits viviparity, a reproductive strategy in wh...
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Molecular Digitization of a Botanical Garden: High-Depth Genome Sequencing of 689 Vascular Plant Species
Genome sequencing has transformed plant research, offering insights into species diversity, evolution, and adaptation...
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Chromosome-Level Comparative Analysis of Brassica Genomes
Brassica species are essential for agriculture and evolutionary studies, with genomes shaped by polyploidization even...
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Draft Genomes of Five African Orphan Crops: Expanding Genetic Resources for Food Security
To diversify global food supplies and enhance nutrition security, underutilized crops—often referred to as orphan cro...
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Chromosome-Level Genome Assembly of Spotted Sea Bass
The spotted sea bass (Lateolabrax maculatus) is a commercially valuable fish widely cultivated in China. Despite its ...
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Chromosome-Level Reference Genome of the Siamese Fighting Fish
The Siamese fighting fish (Betta splendens) is well known for its highly aggressive behavior, making it a valuable mo...
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Population Genomics of Japanese Quail: Insights into Genetic Diversity and Domestication
The Japanese quail (Coturnix japonica) is a poultry species with significant agricultural and scientific value. As a ...
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Pearl Millet Genome Sequencing: A Resource for Improving Agronomic Traits in Arid Regions
Pearl millet (Cenchrus americanus) is a staple crop for over 90 million farmers in arid and semi-arid regions, partic...
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Genome Sequencing of the Pearl Oyster *Pinctada fucata martensii*: Insights into Biomineralization
Pearl-producing mollusks have long been recognized as economically valuable species, not only for their exquisite pea...
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Draft Genome Sequence of the Tibetan Medicinal Herb Rhodiola Crenulata
Rhodiola crenulata (R. crenulata) is a highly valued medicinal plant, particularly in traditional Chinese and Tibetan...
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Genomic Basis of Alternative Reproductive Strategies in the Ruff
The ruff (Philomachus pugnax) is a migratory wading bird with one of the most complex and fascinating mating systems ...
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Nature Biotechnology: Decoding the Upland Cotton Genome and Its Polyploid Evolution
Our 2015 study in Nature Biotechnology presents the first high-quality assembly of the cultivated Upland cotton (TM-1...
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Genome Draft of the Legless Anguid Lizard *Ophisaurus gracilis*
The transition from lizard-like to snake-like body forms represents one of the most intriguing evolutionary transform...
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Genome Sequencing of Phalaenopsis equestris: Unraveling Orchid Evolution and Floral Diversity
Orchids are one of the most diverse and fascinating plant families, displaying remarkable floral adaptations and ecol...
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Comparative Population Genomics Reveals the Domestication History of Peach
Peach (Prunus persica) is one of the most economically and culturally significant fruit crops, with a long history of...
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Genomic Variation Map of Cucumber: Insights into Domestication and Diversity
Most fruits consumed today are the result of long-term domestication and breeding efforts. However, the genetic basis...
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Genomic Landscapes of Chinese Hamster Ovary Cell Lines and Cricetulus griseus
Chinese hamster ovary (CHO) cells are the preferred production hosts for biopharmaceuticals, widely used for the deve...
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Foxtail Millet Genome Sequencing: Insights into Grass Evolution and Biofuel Potential
Foxtail millet (Setaria italica) is a drought-tolerant crop with rich nutritional value and historical significance, ...
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Nature Genetics: Maize HapMap2 Unlocks the Extensive Variation in a Genome in Flux
Our 2012 study in Nature Genetics characterized 55 million SNPs across 103 maize varieties, providing a transformativ...
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Nature: The Tomato Genome Sequence Decodes the Evolution of Fleshy Fruits
Our 2011 study in Nature, as part of the Tomato Genome Consortium, provides a high-quality reference genome of tomato...
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Resequencing 50 Accessions of Cultivated and Wild Rice for Agronomic Gene Identification
Rice (Oryza sativa) is a staple food crop that has undergone extensive domestication, resulting in significant phenot...
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Nature Biotechnology: Decoding the Genomic Blueprint of the Biopharmaceutical Workhorse - CHO Cells
Our 2011 study in Nature Biotechnology presented the first draft genome of the CHO-K1 cell line, providing a transfor...
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Resequencing 31 Wild and Cultivated Soybean Genomes: Insights into Genetic Diversity and Domestication
Soybean (Glycine max) is a critical crop globally, serving as a major source of protein and oil. Understanding its ge...
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